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Irish term that a woman (or man in special cases) says when they are having sex with a man named Brian.
Woman/Man: Harder!
Brian: UMPH!
Woman/Man: O Brian!(Irish accent)
O Brian by asdklfj! March 25, 2009

o’brian 

Hi I am a person and my name is o’brian . Okkkkk

o’brian 

O’brian, what am I going to do with you?
o’brian by Hannah230 May 6, 2025

Dylan O'Brian 

If you just typed this in thinking that his name was actually spelled that way, then you need to stop and re-evaluate your life please and thank you.
- "Omg I love Dylan O'Brian in Teen Wolf!"
- "It's spelled O'Brien you fucktard."

conan o'brian

the incorrect spelling of conan o'brien, a popular late night talk show host.
-"dude, i LOVE conan o'brian"
-"oh really? well then shouldn't fans be able to spell his name correctly?"

its conan o'briEn, people!
conan o'brian by emmyloo July 5, 2006

Conan O'Brian

The best Late Night Talk Show Host. Ever. If you disagree I will hurt you.
Conan airs on NBC weeknights at 11 PM CST