Refers to threads on a screw, nut, bolt, etc. To tighten, you turn to the right (clockwise). To loosen, you turn toward the left (counter clockwise). A few exceptions exist, notably old propane cylinders and some pipe fittings.
A multi-layered toilet treat akin to a nice meaty lasagne dinner. You can celebrate a 'Loosagne' after taking a poop and commencing the wipe action. During wipe-time the need for another poop ensues leading to a second shitty layer being neatly placed on top of the paper, and so the cycle continues. Anything more than 2 poop layers and you can consider yourself a Loosagne master. The cheesy topping is optional, but highly recommended !