little hommie Share definition Flag a thug ass muthafucka who knows how to smoke weed and keep a heap of it most of the time. hey dude little hommie is aweome dont say that to him he can kick your ass and im not helping you. little hommie by chris quaffy February 2, 2010 0 0 Get merch Get the little hommie mug. Buy Now — $32.95 See more merch