A condition in which a person has multiple STDs. Usually acquired by promiscuous fucktards who refuse to use condoms during intercourse. Used to signify how nastysomeone is.
I heardJohngot herpagonosyphilaids from all those hooknasties.
A combination of Herpes, gonorrhea, syphilis, and aids. Usually the first thing someone thinks of when they think about a really slutty girl/guy they don't like.
Guy - "Hey Suzy, do you know that hot chelsea chick that sits behind us in biology?"