gone south 

When a situation, person or animal gets out of control, crazy or bad. crazy we need to talk skank Mardi Gras

The milk in the fridge has definately gone south.

That skank has gone south on me!

Man, I am goin' south this weekend

gone south by ahmed zahir February 10, 2007

Gone south of retarded 

When something is worse than what it was prior

I've gone south of retarded after my forth bottle of Cisco

Gone south of retarded by mts666 November 12, 2009

Shit Has Gone South 

When shit goes south, it goes from bad to worse.
Basicaly, when it goes south, everyone involved is fucked.

Guy 1 : Shit has gone south!
Guy 2: FUUUUUUUUUUUUUUUUU

Shit Has Gone South by Geoff K July 27, 2011

he's gone south 

A phrase to define someone with downs syndrome, or "has gone south"

Paul : eeaarr lad look at that same head over there

Mike: Anno yeah he's gone south !

he's gone south by dreadiroth August 27, 2009