When a situation, person or animal gets out of control, crazy or bad. crazy we need to talk skank Mardi Gras
The milk in the fridge has definately gone south.

That skank has gone south on me!

Man, I am goin' south this weekend
by ahmed zahir February 9, 2007
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A phrase to define someone with downs syndrome, or "has gone south"
Paul : eeaarr lad look at that same head over there

Mike: Anno yeah he's gone south !
by dreadiroth August 27, 2009
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When shit goes south, it goes from bad to worse.
Basicaly, when it goes south, everyone involved is fucked.
by Geoff K July 27, 2011
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