Fuck My Mother Fucking Life. Used on special occasions, when you really fuck up or you just get fucked.
I've just got two speeding tickets, two parking tickets, fired from my job, kicked out of school, and arrested because my license plate didn't match my old registration. FMMFL!
When you have to pee in a movie but don’t want to miss anything, and must do the following mental equation: will the amount I have to pee cause enough discomfort to diminish my attention capacity for the remainder of the movie to an extent which is greater than the amount of the movie I would miss by making a mad dash to the restroom.
I saw Satantango last night, wonderful film but by the 5th hour I had to start doing pee calculus.
Short-hand for the word floccinaucinihilipilification, meaning the estimation of something as valueless (encountered mainly as an example of one of the longest words in the English language).