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One Eye Up 

Keeping an eye open. Watching out. Being aware.
And "trust" is a word you seldom hear from us
Hustlers we don't sleep we rest one eye up

-Jay Z, "December 4th"

one eye up the chimney 

A person with eyes that look in different directions from each other.

Sometimes it happens after a person gets very intoxicated.
When Mandy sits down to watch TV she has one eye on the

TV and the other eye is up the chimney.

Simon got so pissed he's got one eye up the chimney.

eye throw-up 

the antonym to eye candy. something unpleasing or offensive to the eye.
That guy is total eye throw-up
eye throw-up by aimalive February 20, 2009
The look recieved when your partner is performing a blow job, and you gaze in her eyes while receiving it.
She can suck a dick it tell ya, and looks cute giving me that up-eye.
Up-eye by big brains April 12, 2021

Go pound sand up the eye of your cock 

Extended, modified version of the traditional expression "go pound sand", use this version when you really want that special someone to fuck off.
Dave: Dude, you owe my 5$!

Kyle: Dave, I don't have your money, go pound sand up the eye of your cock.

tell your eye to wake the fuck up 

A rude insult you make to someone who has lazy-eye or is cross-eyed
Mike: Bro you got shit in your eye!

Dan: Don't even start me with your eyes! Tell your eye to wake the fuck up