Someone who is a butthole but very holy at the same time.
Ex: the pope was being a huge buttholio early today.
by buttholio-creator July 17, 2013
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Another term for an asshole. An assholio. Don't be an assholio.
You Buttholio!! You ate my nachos!

"The buttholio" likes to act like an asshole, he or she will do shit to piss you off.
by Sahalee5 November 27, 2013
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An RFP issuer who expects turnaround over holiday weekends and in time frames that is unreasonable. Stems from a belief that being task demanding will yield better results - often, no always wrong.
Mr.K. is a Buttholio!
by James Consultant August 31, 2006
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a mythical creature of mexican canadian decent known for its abnormally sized foot and distinct ballchinian resemblence, however unseen to the naked eye due to a patch of fur directly over the tail bone is the legendary feature from witch it draws its name, her second butthole is discretely placed right atop the seperation of the gluteus maximus muscular insertion (aka, buttcrack) and most notably she is known for her distinct symphonic gastric releases, as harmonic and enchanting as it is deadly, to this day there is only one known to be in captivity and has been given the human friendly name of jessica white to as not detour the curious from her splendor and overall gentle nature, in all dos buttholios is a creature to be respected, repopulated and maybe one day accepted into our comunity to live as one with a more intellegent and sophisticated mammal like us humans
did you hear that? sounds like two winds colliding, it's beautifull... wait! thats not the song of the forest, it's dos buttholios!!
by stuju666 January 27, 2011
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An epithet that stems from that of the popular magician Harry Houdini (Ze Great Houdini). This comical phrase is growing in popularity on the east coast, and is most frequently employed when the speaker wants to achieve a hilarious non sequitur.
Stephen: "Hey, Fernando, have you done the math homework yet?"

Fernando: "I am Ze Great Buttholio!!"
by OldPossum May 24, 2011
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Buttholio (pronounced butt-hole-ee-oh) is a nicer way of calling someone a butthole, but it’s still an insult.
Buttholiol (pronounced butt-hole-ee-ole) is actually a compliment!
Example sentences for buttholio/buttholiol:
“I hate you! You’re a buttholio!”
Thanks so much! Your a buttholiol!”
by Leila the Cat February 24, 2021
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when you intend to joke about a butt, but you don't want people thinking your weird.

someone who is trying to be funny and is being super rude, but you don't want to be rude back because you know how annoying they get when they don't get their way.
1) "that chick's buttholio doesn't look symmetrical. does she have buttholio cancer?"
2) "my neighbour never leaves me alone. what a buttholio."
by 5 fingers up my ass September 16, 2023
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