YOFO

You only fuck once

E: OMG, that wedding was so fun! I'm so happy for them.
J: Yeah, but I totally heard the bride and groom YOFO'ed... Poor girl.
E: Oh man, no YOFO. Never YOFO!

by Paperscissorsrockme September 12, 2013

YOFO

You only flunk once...

You can and will only flunk photography once.. YOFO

by yeeaaahhbuddy June 01, 2012

YOFO

The YOFO 🤟🖕, or better known as the "Yo, fuck off", is an action of supreme consciousness where the person performing the YOFO shows the receiver the "Yo" symbol (an upward facing spiderman gesture 🤟) followed by a instant change to the holy middle finger🖕.

Beta female - "Oni-chan, uWu :3"
Sigma male - YOFO 🤟🖕

by NikkuR January 07, 2022

Yofo

latin slang for vagina

White guy: yo dude, did u see that girl?

latin guy: si vato, tenia una mini skirt y se le miraba todo el yofo!

White guy: que?! O.o

latin guy: la Pussy guey!

by Torched Up: JoJo ThunderBoltz April 08, 2010

top over the pop mock yofo

to top something you recently did with something even better, thus giving people something to look forward to.

Are you going to top over the pop mock yofo your gig next year and give an even greater concert?

by HyggeligKar December 22, 2007