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Means "You Only Lotus Once".

Lotus referring to the giant lotuses on Christofer Drew's butt. But of course, Christofer defies the law and lotuses twice.
Hipster Chick: Y.O.L.O!

NSN Fan: Christofer Lotuses twice.

Hipster Chick: The fuck?

NSN Fan: Ugh, just go away.
Y.O.L.O by lovethelotus May 17, 2012
Acronym for You Only Live Once.

Now get off your computer and go outside.
George came to the party with the word Y.O.L.O. on his shirt and got things started.
Y.O.L.O. by THC420 December 27, 2009
Drake fans: you only live once.
Christofer Drew fans: you only lotus once .c;
Christofer Drew: make fun of my lotuses and ill eff you up .c; Y.O.L.O.
Y.O.L.O. by haiguise May 17, 2012

Y.O.L.O.U.Y.A.C.T.Y.L.N.T 

you only live once unless your're a cat then you live nine times
Person A: you only live once
Person B: HAHA my cat lives nine times

Both: Y.O.L.O.U.Y.A.C.T.Y.L.N.T

Y.o.l.o.b.e.f. 

You only live once but eternity's forever.
Person 1: That was insane, even better when I screamed Yolo!

Person 2: Dude, you almost died. You better think Y.o.l.o.b.e.f. before next time. Don't risk it for a temporary biscuit.
Y.o.l.o.b.e.f. by 76Steve June 24, 2023