Xboxistis 

When someone has been playing the xbox for too long and starts to glow green resulting in the xbox logo forming in their eyes and the person looking like they are hypnotised by the screen in front of them.

"Doug is off school again today!"
"Didnt you hear? He has Xboxistis!"

Xboxistis by Oliver Kerry December 29, 2007

xboxosis 

A Lack of a soul due to the constant playing of an xbox 360. The soul becomes seperated from the host and lives in the harddrive.

Joe died last night because of xboxosis. I told him he should stop playing.

xboxosis by nathan the reaper March 31, 2008

Xboxitis 

Cramping, stiffness or pain in the fingers and or hands associated by the overuse of an Xbox console controller. Especially the trigger (Pointer) finger.

Pronunciation: Xbox-itis

My trigger finger hurts so bad from gaming too long, I think I have “Xboxitis”.

Xboxitis by The Southern Yankee June 18, 2018