Xboxitis 

Cramping, stiffness or pain in the fingers and or hands associated by the overuse of an Xbox console controller. Especially the trigger (Pointer) finger.

Pronunciation: Xbox-itis

My trigger finger hurts so bad from gaming too long, I think I have “Xboxitis”.

Xboxitis by The Southern Yankee June 18, 2018

Xboxistis 

When someone has been playing the xbox for too long and starts to glow green resulting in the xbox logo forming in their eyes and the person looking like they are hypnotised by the screen in front of them.

"Doug is off school again today!"
"Didnt you hear? He has Xboxistis!"

Xboxistis by Oliver Kerry December 29, 2007

x-boxitis

Calling it sick for a day to get some more quality time with a sweaty 360 controller instead of going to work or school.

Darlington: Hey, where's Baje?

Me: $10 says it's x-boxitis. He said something about hitting the CoD5 yesterday.

Darlington: Does he need a get well soon card?

x-boxitis by Deuce"Nurgen"Devine January 28, 2009