whats up with that 

One of the funniest series of sketches Saturday Night Live have ever made.
Seriously search "Whats up with that snl" on Youtube

Kenan Thompson "Ooooh yeah, Whats up up with that, whats up with that"

whats up with that by Naughtopus June 11, 2018

Whats up with that 

Something that is non uderstandable

you see a rich guy in a toyota
"whats up with that"

Whats up with that by hey my mom April 5, 2010

what's up with that

A phrase used to ask about something odd, or what the point of something is. The word "that" can also be replaced with whatever noun the person is asking about. It is also common to inerject the word "fuck" into the phrase to express shock or discust.

What's up with the smirk?
Look at all those bags on the road. What's up with that?

Person1: What the fuck's up with your hand!?
Person2: Ahh! Why are you just standing there?! Take me to the fucking hospital!

what's up with that by Cinymin86 November 16, 2009

what's up with that

A phrase used after hyping someone up.

You been on your fitness lately. What's up with that?

what's up with that by BEYONDaverageguy March 2, 2021

What is up with that

What you say when you do not really know what to say.

Bill: "hey look at that"
Ted: "what is up with that"

What is up with that by nellaws September 24, 2003