When something is described by the media or any large number of the uninformed populous as something huge and important if not something terrible and earth shattering (i.e. Swine Flu) and it fails miserably to live up to expectations.
This is derived from the modern version of Battlestar Galactica where Kara Thrace was described as "the Harbinger of Death" when in fact she had little effect on the ending of the show and just vanished mid conversation.
Yeah, don't worry about swine flu, its not that deadly, it is an example of Kara Thrace Syndrome.
What do you mean? People died!
Yeah, but only about 200. Thousands die each year from the regular influenza. Big deal.
Short-hand for the word floccinaucinihilipilification, meaning the estimation of something as valueless (encountered mainly as an example of one of the longest words in the English language).
Precedes or follows either a gratuitously disrespectful or honest remark, originated in New York City. Used in similar fashion to "no offense" or "to be honest," interchangeably.
Ya mans is wild buns, respectfully. Respectfully he's washed.
After school, The Modells on Jamaica Ave was active. Respectfully.