Top definition
1. When someone tries to do something, usually with multiple attempts, and fails

2. Leaving somewhere, usually with haste
"I tried to talk to the bartender but struck out"

"He struck out as soon as he heard the guy was coming that he owed money to"
by Nesta86 May 15, 2013
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2
When you try to get through the bases but it ends before 4th base
Guy 1: I got to second base with Julia last night but I struck out
Guy 2: Man that sucks
by Jeicex1 January 03, 2019
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