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1. When someone tries to do something, usually with multiple attempts, and fails

2. Leaving somewhere, usually with haste
"I tried to talk to the bartender but struck out"

"He struck out as soon as he heard the guy was coming that he owed money to"
by Nesta86 May 15, 2013
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Aug 11 Word of the Day
You can tell by the way she walks, she got that WAP.

You can look at her face and tell she ain't got that WAP.
by Black Don August 06, 2020
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When you try to get through the bases but it ends before 4th base
Guy 1: I got to second base with Julia last night but I struck out
Guy 2: Man that sucks
by Jeicex1 January 03, 2019
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