Sluttybutt Share definition Flag A skanky & flirtatious usually drunk female who thinks she is the shit but truly is a known hoe. That girl is a drunk mess she has been all over all these guys all night, what a sluttybutt! Sluttybutt by abouttime June 3, 2009 0 0 Get merch Get the Sluttybutt mug. Buy Now — $32.95 See more merch