Santonyo 

Santonyo is a real street nigga he don't give af about a deal. Lost his dick in an explosion, AkA master mind behind the death of 2 pac

Boy you better gone with yo Santonyo lookin ass

Santonyo by Tonefrmdablock June 18, 2018

Santonio 

The most awesomest person ever that comes up clutch when the pressure's on.

Person 1:Hey, look at that kid! He's so cool!
Person 2: Yeah, he's a regular santonio!!

Santonio by BlackandGold123456 May 25, 2009

Santonio Holmes

The MVP of the 2009 NFL Super Bowl.

Wide Receiver for the Pittsburgh Steelers out of Ohio State University.

Made the game winning catch with less then a minute left in the game to put the Steelers in the lead 27-23.

That catch by Santonio Holmes was so amazing, no wonder he won the MVP!

Santonio Holmes by Peter Ol February 1, 2009

Santonio Holmes

To make an incredible save or bail out, like Santonio Holmes did in Super Bowl XLIII.

"Dude, we were so almost busted last night."
"Really? How did you get out?"
"Ah, Grant pulled a Santonio Holmes."
"Nice!"

Santonio Holmes by superbowlxliii February 4, 2009

santonio miller 

A light skin person with the name Santonio Miller is strong, cute always comes in cluch also known has a stoner but is also a Fuxkboy

That person getting my nerves I’m go Slam them like Santonio Miller

santonio miller by Fuxkboycentral November 7, 2019

Santonio 

That Nigga perriodtttt

This is a santonio right there

Santonio by anonymous November 23, 2021

santonio turner 

Santonio turner.. the best friend in the whole wide world that's got you're back no matter what !he's great in every which way and is a beast in sports!! Hes always there for you no matter what and when you need all you need to do is ask after all he is the best broski in the world.

Dang look at Santonio turner go again! # 59 scored another touchdown and he cured his best friends heart right before the game!

santonio turner by Curly fries. August 15, 2017