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A trashy bitch. A melspo is a slut on another level of sluttiness. She is the female fuckboi. If you ever come in contact with a melspo, save yourself and run the other direction. A melspo will TRY to hook up with anything that breathes.

A Melspo will always go for the classy guys first, however when this does not work, she resorts to lesser men. It is common for a Melspo to attemp to steal a classy guy (that is unique, good at sports, funny, really smart) that should be with a girl that has equal class.
Guy 1: That girl is trashy and a serious slut!

Guy 2: Dude, she's a total melspo.
Melspo by MelonBlanket September 12, 2016
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Melpo Mene 

an independent band formed and headed by musician Erik Mattiasson from Stockholm, Sweden.

Discography:
-Holes (2004)
-Bring the Lions Out (2008)
-Behind the Trees (2012)

The single "I Adore You" (from "Bring Lions Out"), was used in a 2008 Volvo car commercial.
- Can you name all nine muses?
- Well when Melpo Mene started to release soundtracks for the motion movie where all muses were named, i learnt all of them
Melpo Mene by annalotte August 15, 2012
Related Words
A last name of the Superior of all family’s. They know how to have a laugh and there always talking. This family is very close to all its members.
Person 1: “Wow have you seen that family, they seem fun!”
Person 2: “Yeah, that’s the Melson family, there the best!”
Melson by Lammy109 February 12, 2021
A girl that is extremely messy and has temper tantrums
Messpot by Dipshit26 April 1, 2019

Mt Messpoovius 

When you take a shit above the waterline, get up and pee on it so it looks like a volcano.
It was hard as shit holding my urine in when I was creating a Mt Messpoovius
Mt Messpoovius by Tweezedout January 4, 2017

(noun) A center point where bits and liquids
tend to run together and become indistinguishable.

variation of "melting pot"
Waving his hand over the middle of my soggy plate of
mashed potatoes, gravy and peas, my brother said, "Don't
forget to eat your melpo."
melpo by msCobby October 2, 2005
A masturbation sock named after the girl of your desires. Invented by a wise man of legend named Logan.
My Melsock is so dirty, I cocked it to death last night.
Melsock by Fatjesus September 13, 2014