Jennifer Aniston Syndrome

When you are a fairly attractive person but you can't seem to maintain a relationship regardless of how attractive you are.

SUE: My boyfriend broke up with me. I thought we had a great relationship. I don't understand why I can't manage to stay in a good relationship.

LORI: Girl...you got Jennifer Aniston Syndrome.

by not4uboy August 21, 2010

Jennifer Aniston Syndrome

Noun.

When you seem to not age at all or even age backwards. Usually by way of plastic surgery.

Rebecca: Wow! You actually look younger than the last time I saw you!

Sheryl: Well, I did get diagnosed with Jennifer Aniston Syndrome

by HorseJerky1776 January 05, 2020