1 definition by not4uboy

Jennifer Aniston Syndrome

When you are a fairly attractive person but you can't seem to maintain a relationship regardless of how attractive you are.

SUE: My boyfriend broke up with me. I thought we had a great relationship. I don't understand why I can't manage to stay in a good relationship.

LORI: Girl...you got Jennifer Aniston Syndrome.

by not4uboy August 21, 2010