in the game 

when someone is actively participating in organized crime or generally committing criminal acts as a source of income. Also used to refer to an individual as "not being in the game." Commonly used to refer to someone after they died in ways related to their criminal activities.

He knew the risks of the job, he was in the game.

She got killed in the crossfire but she wasn't in the game.

in the game by hoodyFPS May 29, 2021

In the game 

British slang for prostitution

He had no idea his mum was in the game.

In the game by Itgal23 January 24, 2021

in the game 

when someone is intoxicated. Also known as "drunk, turnt, or gone".

Dude, I drank so much last night. I was in the game.

in the game by agame123 December 14, 2015

all their skin in the game

This describes a situation in which someone is risking everything.

The bomb squad has all their skin in the game defusing the van.

all their skin in the game by I, Wreckerrr December 2, 2016

best teeth in the game 

Anthony Fantano, "The Internet's Busiest Music Nerd".

Melon has the best teeth in the game.

best teeth in the game by Sebastion Wheeler January 16, 2018

fucked in the game 

1. In a bad situation with no way of getting out; catch-22.
2. Loosely meaning beaten or defeated by some obstacle in life
3. Between a rock and a hard place.
4. A song by rapper Spice 1.

"He has a test he ain't studied for? Oh well, I guess he just fucked in the game."

fucked in the game by PM123 August 4, 2007

skin in the game 

To have a personal stake or investment. Originally coined by Warren Buffett

Why do you care what Apple's stock is, you have no skin in the game.

skin in the game by CatIsWrongAboutThis.JPG December 5, 2013