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1) If you hear someone say "hey oh" you have to say it back.
A greeting.

2) When someone says "hey oh" in a large group of people, everyone has to reply by saying it back.
Usually used jokingly after something raunchy is mentioned.
Example 1:
Person 1: (name)!
Person 2: hey oh!
Person 1: hey oh!
Person 2: whassssssuppppp?!

Example 2:
Person 1: She talks shit behind everyone's back.
Person 3: ... and then she tries to act all nice and shit.
Person 2: I heard she can fit a whole soap on a rope up her cooter.
Person 1: haha, hey oh.
Person 2: hey oh.
Person 3: hey oh.
hey oh by cass! January 9, 2008
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Cocaine. inspired by the Red Hot Chili Peppers song "Snow (Hey Oh)"
"I got your hey oh, now listen what I say, oh"
hey oh by Mr. Ho7987887 January 26, 2012
Often used after or is it...
it is just a way of expression such as like burn or face.
Commonly used by awesome people from wisconsin. Every one joins in on the Hey-oh after Some one says or is it...
It is just for fun
Guamy- im not gay... Or Am I... HEY-OH!
Kevin-......................... HEY-OH!
Hey-oh! by KevZero Pearson September 20, 2007
A reaction to a pick-up line, comeback, burn, or diss that was, at first thought, great, but upon further examination revealed itself to be a) stupid, b) creepy, or c) just plain tragic. Usually starts with great enthusiasm only to die down very quickly.
Guy 1: Boy your mama's so fat they had to use an atomic bomb to make a crater large enough to bury her in!

Guy 2: HEY-oh.
hey-oh by A NONY MOUSE October 21, 2014

hey oh yeah 

hey oh yeah by Anonymous April 3, 2003
The perfect greeting: pleasantly surprised, enthusiastic, casual, and friendly.

Tell a friend "Oh hey!"
Dan: Oh hey!
Robert: Oh hey!
Oh hey by Good cheese June 8, 2018

Oh Hey Girl 

A comment made to a friend/colleague/coworker who is female with an emphasis on the "hey" (Ha-y). Appropriate anytime.

Also see: Oh Hay Gurl
Oh Hey Girl, did you watch The Bachelor last night?

Oh Hey Girl, how was your party?

Oh Hey Girl, guess who just asked to be my friend on MySpace!
Oh Hey Girl by LAS115 May 13, 2007