Hepfecta Share definition Flag One who has acquired all three forms of hepatitis - A, B, and C. I didn't have the heart to tell my friend that his girlfriend had completed the hepfecta during her college days in Detroit. Hepfecta by EBJJBE March 31, 2011 0 0 Get merch Get the Hepfecta mug. Buy Now — $32.95 See more merch