Slang for the headcrabs in Half Life 1 and Half Life 2.
Headcrabs latch onto the victims head and turn him/her into a zombie, hence the name headhumper
Small crab alien from the gamehalf-life/half-life2 they can turn humans into zombies by humping the guy/girls head with its beak (WTF) the were called that in the popular ____'s mind sieries on you tube by Barney the security gaurd
Barney the security gaurd: fuck you tiny crab basterdes I I'm just gonna call you head humpers from now on now were'd you go ... AGH FUCKING HEADHUMPER die die die die die.
Dame you fucking headhumpers