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1. A sexually transmitted disease, most common in thots of all ages

2. A rare disease in which you cannot stop dancing to despacito, also known as "Despaitis"
Ex. "Ey you thot, I hear you've been smashing all the guys in the school. You know you can get despa from that, right?"
Despa by Nothing_Important January 16, 2019

Despa-yeet-o 

It originates from despacito which means depression in spanish and yeet is overly used word so together it is overrated depression in word form.
Ex 1:" Hey kid in the corner, how are you today?"
"Despa-yeet-o."
"Enough said."
Despa-yeet-o by sophia314 January 24, 2019

despa vegito 

Yo that despa vegito video was amazing
despa vegito by Jiryra April 18, 2018

Deepayadi 

Copying a content from your friend and publishing later it as yours.
Ee kavitha Njan deepayadichathaanu..
Deepayadi by Krishna darshan November 30, 2018

Deepayadi 

Copying a content from your friend and publish it as yours.
While writing your examinations no one should deepayadi from others..
Deepayadi by cskd123 November 30, 2018
The opposite of hope. It is something that hope will always defeat.
It is also something Nagito Komaeda dislikes.
We'll never give in to your despair.
Despair by hopebagelko June 30, 2017