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Cross Threaded 

When a person normally drinks alcohol, then tries drinking alcohol and takes weed gummies.
Went to the bar last night and Steve showed up with gummies, I got totally cross threaded.
Cross Threaded by D addy September 12, 2021

Cross Threaded 

When you are taking a crap, and it takes you a long time, and it feels as if a boulder is being squeezed from your ass. It hurts and feels like it's coming out sideways.
You go back to your desk and someone says "dude you were in there a long time", you respond by saying "dude, i had one cross threaded"
Cross Threaded by Jamhole September 29, 2005

Crossthreaded 

Crossthreaded. Mad .upset. pissed off
I don't know what you did but boy is she crossthreaded
Crossthreaded by anonymous July 6, 2021