22s 

Basicly 22s are some hot rims that are 22 inches

Oh! Dats a clean ride wit dem 22 inch spinners. Go head pimp! Yoouu Knooow!!

22s by Ebony January 27, 2004

22s 

Not only do they refer to rims, but also the size of someones arms: usually the Biceps.

Got some 22s right here!

22s by s1yfoxx September 15, 2010

22s 

Those hardcore chrome rims 22 inches in diamiter.

Yo, homey, did you catch them 22s on that dudes car.

22s by Mikhailo July 27, 2003

22s 

A 22-ounce bottle of booze. Often Malt Liquor and Mike's Hard. Popular on College Campuses for their relative cheapness and availiability after 8pm.

Four North Militia cuts loose with 22s, biatch, that's what's up.

22s by PT Zado January 29, 2004

22s on the lac 

a cadilac with 22's

damn look at that lac on 22s

22s on the lac by dumb @$$ October 19, 2003

22s_son 

it means your doin work. getting it done

talking to a friend and you explain what your doing. 22s_son. doin work

22s_son by 22s_son February 22, 2011

22s on the lac 

escalade with 22 inch rims

damn look at the 22s on that lac

22s on the lac by dumb @$$ October 19, 2003