The number of love. When two people fall in love, the number 22 will follow you. If you see a 22, that means that the person you are in love with is thinking about you.
Listening to Love Story at 12:22 in the afternoon.
by 122206 January 19, 2010
the number of princesses
wow look at that princess over there. he most love the number 22.
by theshackisbeastly July 22, 2010
The age after 21 where you realize you still have another 3 years to get your shit together
Haha I'm only 22
by Jeri Lei July 17, 2008
1) A .22 caliber handgun
2) Any rim that measures 22 inches in size
3) Slang term used for women to let you know they are prostitutes.

1) Don't tote no 22's
2) Magnum cost me 22, sat it on them 22's
3) Lil mama super thick, she say she 22

(All examples from Rick Ross' Hustlin)
by TheChef May 1, 2006
At a bar, two men watch as a hot, librarian walks into view. One man looks at the other and says..."check out the 22."
by jjpaige July 12, 2009
A sexual position depicted through numbers (like 69); meaning doggystyle (could be used for anal sex as well).
by SoLux July 20, 2008
The number seen often that symbolizes best friends. When seeing a 22 on random objects or at random times, you should stop and inform your best friend that you are thinking of them.
Best Friend #1: Orders Starbucks and the bill totals $4.22
Best Friend #2: Received a picture on their cell phone of the bill and thinks "Ohhhh, my best friend is thinking of me"
by Kim1Champ August 3, 2010