Nuke 

A hook-up that is so intense, it's of nuclear proportions.

Variations: Nuke it out; Nukin'

Caking, smashing, nailing, boning, etc. all have similar meanings, but none can match the intensity level associated with "nuking."

Paul: "Bro, did you ever end up gettin' with that bitch last night?"
Dan: "Dude. We nuked it out for the longest time, it was unbelievable. I'm gonna try and nuke her again later tonight..."
Paul: "Shit, man...I saw you guys cakin' it but I didn't think you'd actually nuke her."

Nuke by garhcSD January 17, 2011

Nuke 

The (fabricated) designer drug used in the 1991 movie, Robocop 2.
This drug was extremely addictive, and used to alter and control ones mood as one sees fit. It came in several varieties:

Red Ramrod
Black Thunder
White Noise
Blue Velvet

The most commonly used variety being the Red Ramrod.
This drug was popular due to it's strong effects and cheap price. Red Ramrod gave the user a constant high for one to two days before the effects wore off. This drug was designed by Cain, and a scientist named Hank.

Nuke came in a small pod with a needle on the end, and was injected directly into the jugular/neck. Depending on the exact type of Nuke used, effects would differ.

Nuke by Therindos April 9, 2006

Nuke 

Same concept as a hand grenade except these chicks are far worse, and much more disgusting. It is recommended to abort any attempts to associate with any groups of chicks that contain a nuke, since "jumping" on it will not save your friends. It is also highly recommended to evacuate the establishment if a nuke has been discovered as they are highly destructive.

gentlemen #1: "Oh shit, you see that chick over there?"
gentlemen #2 "You mean that grenade?"
gentlemen #1: "That aint no grenade, that's a damn nuke."
gentlemen #2: "Shit, lets get the fuck out of here before that shit goes off."

Nuke by Eazy Money 75 August 26, 2010

nuke 

A word that refers to a Nuclear weapon itself or the action of attacking someone with a nuclear weapon.

Has come to be used in some MMORPG games to refer to attacking a monster with powerful magic spells.

1. Let's nuke the bastards!

2. Our Black Mage just nuked the crap out of that mob!

nuke by Vespasian September 16, 2005

Nuke 

A giant bomb which can destroy a whole city.

Kim Jong-Un is well known for nukes.

Nuke by beluga the suzzi cat November 13, 2022

nuke 

that hXc drug from That Robocop movie thats dealt by the little kid that Robocop can't kill because he's a kid. The horror!

i shot nuke in my dick

nuke by Kid Smelly September 17, 2004

NUKE 

The most popular gay couple in day time television. Luke Snyder (Van Hansis) and Noah Mayer (Jake Silbermann) are the two guys who make up this power couple.

"I WANT NUKE BACK!!!"

"NUKE is so cute"

NUKE by endlessgreen March 2, 2009