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Can be used as:

noun. A crash.
verb. To crash.
Snowflake didn't make that last turn on his bike and wiped out big time!
wipe out by mikwat June 6, 2004
1) Someone who is currently high on Ecstasy ( usually behaving in a fashion to make this abundantly apparent)
2) Someone who regularly takes Ecstasy
Clarke was an obvious wipe out as he continued to munch on his already haemorrhaged inside lip whilst moving his arms like a deranged windmill.
Wipe out by Kaiseraph December 26, 2008
to trip and fall while running. Usually this is caused by tripping over one's own feet, or tripping over an object on the ground, such as a tree branch.
1. Peggy was doing fine running the marathon until she wiped out at mile 14. Fortunately, she just got up and kept running.

2. I hope I don't wipe out in the 5k tomorrow.
wipe out by PeggyWipeOut August 10, 2009

Wipe out the red from my ledger

It's a book-keeping term. Black ink means profit and red ink means debt.
As in reference to "The Avengers" when Black Widow said: "I want to wipe out the red from my ledger"

She feels that if she 'wipes out this debt', she will be free from whatever problem is plaguing her

wipe-out hacker 

A hacker who enjoys wiping out computers after stealing information.
A wipe-out hacker is a piece of human garbage!
wipe-out hacker by Word Madman March 22, 2019

Wipe out tomato town 

To have sex with someone who is on their period
Darren: “yo bro didn’t you stay the night at jens house last night?”

Chad: “hell yeah bro she was on her period tho. But you know I’m always down to wipe out tomato town