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Whatsamattayou 

Basically "whats the matter with you" slurred into one word with an italian accent.
"Whatsamattayou!"
Whatsamattayou by Hazard October 23, 2003

Whatsamattayou 

Saying "What is a matter with you?" in an easy to say catch fraise combining the words "whats" "a" "matter" and "you" to save precious air because we all know that all air will become polluted in a couple years.
Tom- I dont feel so good.

Bob- Whatsamattayou?

Tom- I just told you.

uppa U.S. and whats amatta U. 

I attended whatsamatta U. then went to uppa U.S.

whatsamaddayue 

slang for "what is the matter with you". Often used in Mafia spoofs
Hey Don Tony, you no eat your Z. Whatsamaddayue?
whatsamaddayue by Big Bubba B April 29, 2004

whatsamacallit 

The word you say when you can’t remember the word for it
Anyone know where I put my whatsamacallit?
whatsamacallit by Candji February 17, 2022