To be pregnant.
It was very embarrssing for Kevin when he got Peggy up the duff, but it served him right for trying to save money by using a flak jacket.
by Dunky Oggins December 07, 2003
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by Tsee October 31, 2006
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by 7bandittt January 21, 2021
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An expression of great misfortune, expanded from it's original meaning, to be pregnant. The expansion is due to the expression often being the unfortunate case of the pregnancy being untimely and unpredicted.
"When they find all the coke in Mark's desk, he's gonna be sooooo up the duff!"
"Shit, I've got 2 flats and only 5 minutes to get the airport!"
"You are up the duff mate"
"Shit, I've got 2 flats and only 5 minutes to get the airport!"
"You are up the duff mate"
by Jack Nicholson February 02, 2006
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by TheDuffQueen November 05, 2017
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Guy 1: Damn heathers a come up duff!
Guy 2: Yah she used to be really ugly but now I really wanna date her
Guy 2: Yah she used to be really ugly but now I really wanna date her
by Em's definitions August 14, 2017
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