Tripping or doing something dumb
by Vito June 09, 2017
Somone tripping on a meth high. They are paranoid about staying up for a week straight seeing shadow people and such.
Yo that girl is tweaking yo
by BigPimppin6906 April 20, 2018
A manner of which a person‘s actions and behavior suited them of being very out of pocket and very unorthodox
by Rico gwaap June 01, 2022
by fmoi igb_kvng January 14, 2015
He's so tweaked out.
by kush_ March 16, 2005
Frantic and compuslive behaviour often associated with methamphetamine abuse (crank). People who regularly abuse crank may find themselves unable to stop a particular random activity like searching drawers, having sex, or putting things apart. This is called tweaking.
by RoOophy July 08, 2004
going stupid and/or crazy
by irridpsiclitis May 25, 2019