slooskie Share definition Flag a really slutty and loose girl or possibly a male. one who will slob on anyones knob. Yo, I just hooked up with the dirtiest slooskie at the party. I feel nasty as shiiii bro. slooskie by lilmamag September 15, 2010 0 0 Get merch Get the slooskie mug. Buy Now — $32.95 See more merch