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Ebonics for "sure". Belongs to a group of words that follow the phonetic pattern "eezie". Commonly used as part of the phrase "for sure".
E.g. "Saturday is off the heezie for sheezie. You can find me up in one tweezie" (Welcome to Atlanta).
sheezie by methical May 13, 2006

fo sheezie my neezie 

Fo' Sheezie ma Neezie we be up in her tonite aiight!

For sure my Nigga's we will be staying here tonight, alright!

fo sheezie 

another word for fo shizzle or fo sho means for sure
you goin to dat party lata :: fo sheezie dog::
fo sheezie by bob tg September 13, 2003

shmeezie 

a synonym for the wurd <slut> as in a chick who gets with anyone and everyone esp fo attention, may be shortened to shmeez
Daym, girl, you sh-MEEEEEzie!
Juanita is SUCH a shmeez.
Those classic fit GAP khakis make you look like a shmeezie, my dear child.

fo sheezie 

u holdin down the heezie fo sheezie
(u holdin down the house fo real)
fo sheezie by brittney April 7, 2003

Shebeezies 

A creation of the most likely insane H&H, they started as a phrase, then morphed into coffee beans glued together with broken toothpicks as arms and legs.

Also can be used as a phrase meaning something along the lines of "holy crap."
That tard just poked me with a Shebeezie!

Holy Shebeezies! I've been had!
Shebeezies by Hans le Noir September 26, 2005