quarterbackin' Share definition Flag To Hustle, Slang Yay or Ice on the Block. Dubbed by that man E-40 the Ambassador of the bay. Yo man that nigga right there has been quarterbackin' all night makin crazy ass loot off these tweakers. quarterbackin' by Big Joe AKA that Nagger July 8, 2003 0 0 Get merch Get the quarterbackin' mug. Buy Now — $32.95 See more merch