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permafuck 

An adjective that means you do so many drugs that your brain is permanently fried. You forget how to do easy things, like remember to go to class or put your car in park.
Dude A: Hey dude did you see Cody at lunch today?

Dude B: Yeah dude he's been there for three hours and just got detention for skipping class. He's totally permafucked.
permafuck by poolmaster41 April 21, 2009
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permafuck 

To be in or produce a permanent state of contextual existance in which parties involved are completely and utterly fucked, with no conceivable reprieve and from which there is no escape. See also FUBAR
Guy 1: So how'd your GF know you were cheating? You get ratted out?
Guy 2: No she's got a videotape.
Guy 1: Dude, you're permafucked.

A gangmember rapes a hooker in an alley. Little does he know that the hooker has AIDS. Now he's facing charges of sexual assault, the pimp wants revenge and on top of it all he's gonna die from AIDS in a couple of years. You don't get more permafucked than that.
permafuck by Lord CrutchCricket December 9, 2008

permafuck 

The name of the novel that was featured on the show Weeds. It was written by Andy's crazy ex-girlfriend from Alaska. "Permafuck: A Journal of Spirit Rape"
We are in serious trouble.

I know. We're permafucked.
permafuck by Mark Fredericksen January 13, 2008

permafuck 

Taking a diploma, certificate, license, etc; glueing this to a piece of cheap wood, then covering with a permanent clear coat product. circa 1975
After I graduated from college, my father (permafucked) my diploma.
permafuck by Dr Rob April 19, 2009

permafuck 

To be in or produce a permanent state of contextual existance in which parties involved are completely and utterly fucked, with no conceivable reprieve and from which there is no escape. See also FUBAR
Guy 1: So how'd your GF know you were cheating? You get ratted out?
Guy 2: No she's got a videotape.
Guy 1: Dude, you're permafucked.

A gangmember rapes a hooker in an alley. Little does he know that the hooker has AIDS. Now he's facing charges of sexual assault, the pimp wants revenge and on top of it all he's gonna die from AIDS in a couple of years. You don't get more permafucked than that.
permafuck by Lord CrutchCricket November 22, 2007

Parafucktion 

An instant in which two or more seperate, but equally terrible occurances coincide.
Yesterday, I had a total parafucktion; my hard drive melted down and at the same time the blender burst into flames.
Parafucktion by Althea_Novak August 28, 2007

permahickey

A large party, often marked by lavishness and showiness. Derived from two filipino words of varying dialects - pamanhickan and parmalaiyee, both meaning a pre-wedding get together in which the marrying families discuss their input to the wedding, and hence show how much clout they will carry in the family.
The X and Y families will host their permahickey on Thursday, two nights before the wedding.

When used in a broader sense:
There will be a permahickey at Liberty park for all the residents of the barrio Z.
permahickey by BoobSano December 28, 2009