1)
Adjective -
The ultimate mistake which ends with disastrous
consequences, usually involving multiple parties which were not, directly, involved in the incident. Usually, it starts with a minor, low level, bad decision.
2) Noun - A person who commits the "ultimate" mistake.
The
introduction of the
Africanized Bee in Brazil in 1957 created
consequences that spanned across continents and devastated ecosystems. This is prime example of a "fuck up of the first order".
The person who actually released the bees, or setup the conditions where the bees where released, is also nown as a "fuck up of the first order".