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One Down 

the opposite of one upping someone, trying to match a complaint with and even worse grievance.
Person A: I don't think I did to well on this test!
Person B: Well, at least you studied. I didn't even know we had a test today.
Person A: Why are you always trying to one down me, let me have my moment.
One Down by aly_xandra July 20, 2008

One Down 

It's the rape difficulty in the game payday 2. You'll get swarmed by Zeal-Cloakers, Zeal-Dozer, and skull masked assholes that'll down you in no time. You can be downed only once.
Dummy1:"I wanna try one down"
Dummy2:"No you don't. It'll rape you."
One Down by SniperTon00 May 22, 2018

One Down 

slang for good bye also see one
usually used on communication devices
Poopy: yo ima hit u when i get back to the block iight...one down
Dae Dae: one down my nig
One Down by Rdurbin September 22, 2005

One Down 

AN INDIVIDUAL FROM THIS ESTABLISHED GROUP OF OURS HAS SEEMINGLY LEFT THE CONVERSATION, AND VOICE CHANNEL WE ARE CURRENTLY IN, THUS RENDERING THEM ''DOWN" IN THE SENSE THAT THEY HAVE BEEN 'SHOT DOWN' OR, EXCLUDED FROM THE ACTIVITY WE HAVE PREVIOUSLY BEEN MENTIONED TO BE PARTICIPATING IN - AS A SOLDIER IS 'SHOT DOWN' DURING WAR, RENDERING THEM EXCLUDED FROM THE ACTIVITY - OF WAR - THEY HAVE BEEN ESTABLISHED TO BE PARTICIPATING IN
*User 1 Has Left Your Channel*
User 2: One Down

one-down 

to be less Jewish than one's parents
"Shmuel's parents were good Conservatives, but he one-downed them and only goes to service on High Holy Days."
"Oy vey!"

One down, dawg

Response to inquisitive greeting that denotes you're getting things done (as from a daily list of activities).
Ed: "What's up?"

Alan: "One down, dawg."