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1. A netspeak contraction of the call "no you are", used on messenger services.
2. In the form "noyopic", an all purpose adjective -- can denote swearing, but more commonly with a positive connotation
Person1: "You're such a slag"
Person2: "Noyo biatch"
"Hey, I found a penny!"
by Kirkabelle May 22, 2006
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