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1. A race of mouse-sized and mouse-tailed humanoids from an 80s cartoon series called, The Littles. Little is also the surname of just about every mouse-sized humanoid character in the series. Most episodes centered around the adventures, misadventures, and struggles of two preteen littles.
2. Slang term used by the MPD-DID subculture to indicate child personas of adults who have multiple personalities.
My littles like to watch The Littles.
littles by Downstrike September 25, 2005
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People who are totally awesome in everything they do. There are only two of them in the whole world (plus one dog) Little, Little, and little. Can be cut down to "lil" or "lit" in rushed conversation.
Hey Lit, What's up!

Littles are sooo cute!
Tiny crazy midgets who will yell and attack if having felt threatened by your display of minding your own business or stating your dislike for twilight, wolf's, foxes, roblox, gacha life, etc. Also referred to as "preteens".
Jim: "The littles are watching that overrated vampire movie again."

Reporter: Jim was found dead late last night. Suspects suggest he was killed for a type of ritual to the werewolf gods.
Littles by Neutrisha September 26, 2020

Littles' 

A nickname given to a younger female in a relationship that usually tends to be shorter & most likely petite in stature; But act's just like their male counterpart in the relationship. Like a Mini-Me scenario ;)
Used as a Nickname like "Hey Littles' come here a second." "Or Littles' you see that?"
Littles' by K'Pop713 January 1, 2021

chicken littles 

those delicious little sandwiches that KFC once served, Containing solely, mayonaise, a fried meat square, lettuce, and a bun.
I once ate 48 of those delicious chicken littles.

Chicken Littles 

1. A forgotten KFC offering that only people who were almost born in the 1970's remember.

2. A euphemism for doomsday preppers.
1. Laura really wished that KFC would bring back Chicken Littles.

2. Those Chicken Littles were gathering canned beans like there was no tomorrow.
Chicken Littles by Iamarm January 6, 2014

chicken littles 

I had to shit so bad, I got chicken littles
chicken littles by Jenn October 2, 2004