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don't get your knickers in a twist 

when one gets upset or crazy over something most people think is unimportant
Sally don't get your knickers in a twist over that split milk on the floor, silly Sally!

knickers in a twist 

Agitated, anxious, in a tizz. British, Strine, and New Zealand. Cf. panties in a knot.
Don't get your knickers in a twist. The Frogs are just that way.
knickers in a twist by Octopod November 7, 2003

Knickers in a twist 

Upset or stressed about an issue or situation
the criticism from her boss really put her knickers in a twist.

Kick in the knackers

Kick in the knackers, meaning a kick to the testicles of a male. When a boy is kicked in the cock and balls and it hurts like hell, resulting in the boy falling to the ground in pain and rolling around. A kick to balls/knackers is an unfair move.
Jacob and Harry where fighting at school. Harry would have won the fight but Jacob used a kick in the knackers on Harry and Jacob immediately won the fight as Harry couldn’t continue after having his groin attacked so brutally.

lifes a beach then you get sand in your knickers 

its all fun & games...then not so much...

shit happens...life sucks etc etc...
by the time a woman is 35 she knows lifes a beach then you get sand in your knickers.