A bastardised version of "Fo' sho' nigga", which is a bastardised version of "for sure my nigga", which is a bastardized version of "I completely concur my african-american brother"
Is that your hoe? Nigga she fly.
F'shizzle my n'izzle
Suffix often added following the first consonant of a word to increase the "coolness" of speech. "-izzle" can also be used to replace the last syllable of a word.
How the suffix functions with single syllable words beginning with a vowel (i.e.: up) is unknown.
Origin is said to be from popular African American rapper Snoop Dogg who decided to modify the current English language to increase its ability to convey thoughts, ideas, and expressions.