ho tox Share definition Flag A physical blow resulting in a facial bruising and subsequently blamed on a cosmetic procedure person 1: Will you look at the black eye on Nikki, she claims she got Botox yesterday Person 2:What really happened is she pissed off Jody last night and he gave her a shot of ho tox ho tox by ezreit July 30, 2010 0 0 Get merch Get the ho tox mug. Buy Now — $32.95 See more merch