guapita Share definition Flag "Guapa" is a Spanish word for "pretty," but the "-ita" makes it a term of endearment. So, you'd only say it to/about a pretty girl you really care about. Oye, guapita, you look *hott* today! guapita by b-a-g April 10, 2011 0 0 Get merch Get the guapita mug. Buy Now — $32.95 See more merch