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Its a apparently meaningless word, created by the Spanish comedian Chiquito de la Calzada that became part of the collective language and recurrent in the Spanish jokes slang. Its a funny world by itself and can be replaced by any meaning. Specially funny when replacing sexual words or when being used to insult somebody in a funny and friendly way
that woman is naked you can see all his his down fistro

that man is touching his sexual fistro

i dont believe your tales you are such a fistro
fistro by musero June 3, 2011
Related Words

FistRoast 

1. Where a male will be given a blowjob by a girl, whilst he fists her vagina/anal hole.

2. Where two males fist a girl, one in the mouth and the other in the vagina/anal hole.

First coined by the infamous Shy*.
Shy*:I want to fistroast Jessia Alba.
Others: Holy shit !!
FistRoast by shy* April 7, 2008

Fishrodding 

Fishrodding is when you have sex with a prostitute.
Guy 1: Dude, I bought a prostitute last night for my birthday
Guy 2: You went fishrodding?
Fishrodding by GajeelRedfox June 22, 2019