dufiss 

Alternate spelling of dufus, doofus, etc.
To be an idiot, stupid.

What a dufiss.
You can educate a retard, but no one can help a dufiss.

dufiss by Elle January 27, 2005

defission 

n. The state of a relationship with a friend or loved one when their adamantly untreated depression becomes so burdensome that the relationship is threatened to the point of explosion, resulting in a separation. origin: an amalgamation of depression and fission.
n. The depression, worry, frustration and angst resulting from a friend or loved one's own depression, centering around your desire to help and their rejection of your help, and the feelings of sadness and helplessness you feel as the relationship suffers or even ends as a result.
v. The process of destruction of a friendship or relationship with a loved one due to their intolerable and miserable attitudes and behavior resulting from their long term, untreated depression.

"Pete and I are sinking into defission because no matter how hard I try to get him to think positive or make some positive changes in his life, he still refuses to even acknowledge that he is depressed, never mind get treated. It's like he wants to be miserable, and I just don't want to be around that kind of negative energy."

"I'm starting to feel defissioned because Sally is mad at me again for not being supportive and attacking her when I suggest that maybe it's not that people are being mean to her all the time but that her perceptions are warped from her long term depression and she really needs to treat that to solve the problems."

"Joe and I aren't talking anymore, everything is defissioning because he refuses to get his shit together and go to the frickin doctor!" (colloquial)

"Dude, you have two options: defission with all your friends, or go get help."

defission by high art February 7, 2010

dufass

Portmanteau of duffus and dumb ass.

Graeme, you are such a dufass.

dufass by Richiebres November 3, 2013

dumiss 

a dumiss is a penis... i made it up in the summer when i was under the influence of drugs.

my dumiss is 10 inches long

dumiss by post mike December 12, 2008

dufuss 

A dope, idiot, dummy. It's used not so much as a deep condemnation of character, as commentary of an incident or discrete act. And, meant to disparage the person at that moment for what occurred.

I appreciate that on yahoo it was noted that it's necessarily a mean thing to say

also dufus..........dufəs

I am such a dufuss. Every year I forget my Irish Aunt Trish's birthday, and have to ask my mother-in-law if it's exactly on St Patrick's day.

Happy birthday Trish

dufuss by grubecnerwal July 22, 2016

Dulisse 

a girl who frequently takes loads in her face and enjoys it.

yo, i got with that dulisse chick last night. totally busted a load in her face.

Dulisse by givr October 18, 2009

dufinsmurf 

A fart that comes out of your penis.

Guy 1: Hey that guy just dufinsmurf'd

Guy 2: ewww that's so gross

dufinsmurf by wetduck2 April 17, 2014