calorie coma Share definition Flag When you eat so much that you descend in a state of lethargy so smothering that you you are too tired to even change channels with the remote I'll be here on the couch, I just had two triple cheeseburgers, I'm in a calorie coma calorie coma by Fatburgerwithcheese January 19, 2011 Get the calorie coma mug.